General Cell Based Assays
Cayman Chemical UbIquInon asy Reagent 100uL
An alkaloid with enzyme inhibitory activity an inhibitor of AChE BChE and prolyl endopeptidase (IC50s 281 911 and 907 UM respectively)
Abcam Lovastatin (Mevinolin), HMG-CoA reductase inhibitor, 50MG
MW 404.5 Da, Purity >98%. Potent, competitive HMG-CoA reductase inhibitor (Ki = 0.6 nM). Blood-brain barrier permeable. Inhibits in vivo and in vitro cholesterol biosynthesis. Also reduces α-synuclein levels in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical Lactate Cofactr MIxture 1ea
A derivative of cytidine has been found as an RNA modification in Archaea bacteria and eukaryotes
Revvity Health Sciences Inc HTRF Human Total eNOS Detection Kit, 500 Assay Points
The Total eNOS kit is designed to monitor the expression level of cellular eNOS (endothelial nitric oxide synthase), and can be used as a normalization assay for the Phospho-eNOS (Ser1177) kit.
Meso Scale Discovery U-PLEX Human MCP-3 Assay, Single-Analyte, 96-well plate, LLOD 0.79 pg/mL, Dynamic Range 0.79 - 5000 pg/mL, Uses human serum, plasma, cell culture supernatant
The U-PLEX Human MCP-3 Assay from MESO SCALE DISCOVERY offers a robust solution for the quantitative measurement of human Monocyte Chemoattractant Protein 3 (MCP-3/CCL7). This assay is designed for research applications in immunology and inflammation, providing sensitive detection across a wide dynamic range of human biological samples.
- High quality and ease of use with validated components
- Enables precise quantification of human MCP-3, crucial for inflammatory response
- Validated for diverse human sample types, including serum, plasma, and cell culture supernatant
- Features a low limit of detection at 0.79 pg/mL
- Wide dynamic range of 0.79 - 5,000 pg/mL for various concentrations
- Single-analyte format optimized for dedicated MCP-3 measurement
Sartorius iQue Membrane Integrity Kit
Three dye options gives you more ways to measure cell death.No wash protocol just add and read for fast easily automated workflow.Multiplex with other IntelliCyt kits like Cell Cycle for richer content.PrincipleThe Cell Membrane Integrity dyes are fluorescent molecules that are cell impermeant. Healthy cells with intact cell membranes will exclude the dyes. Unhealthy cells with compromised membranes will allow entry of the dye into the intracellular space. Upon entry to the cell the dye localizes to the nucleus and binds to DNA by intercalation.
Cayman Chemical NBD-Fructose 500UG
A fluorescent derivative of fructose; has been used to monitor fructose uptake by the GLUT5 transporter in MCF-7, MDA-MB-435, and MDA-MB-231 human breast cancer cells; ex/em = 472/538 nm, respectively
Cell Biolabs Inc CytoSelect™ 24-Well Cell Migration Assay Kit (3 µm, Fluorometric), 12 assays
Chemotaxis, a type of cell migration, is a highly integrated, multistep process that orchestrates embryonic morphogenesis, tissue repair and regeneration. The initial response of a cell to a migration-promoting agent is to polarize and extend protrusions in the direction of the attractant; these protrusions can consist of large, broad lamellipodia or spike-like filopodia that are driven by actin polymerization and can be stabilized by extracellular matrix (ECM) adhesion or cell-cell interactions. The CytoSelect™ Cell Migration Assay Kit utilizes polycarbonate membrane inserts (8 µm pore size) to assay the migratory properties of cells. The kit contains twelve 3 um polycarbonate membrane inserts in a 24-well plate, through which migratory cells are able to pass. Cells are quantified using the provided fluorometric dye. The 3 µm pore size is optimal for measuring the migration of leukocytes.
Bioassay Systems EnzyChrom™ Pyruvate Kinase Assay Kit. For quantitative determination of pyruvate kinase activity and evaluation of drug effects on PK activity.
For quantitative determination of pyruvate kinase (PK) activity and evaluation of drug effects on PK activity. Key Features: Sensitive and accurate. Linear detection range in 96-well plate: 0.1 to 50 U/L for colorimetric assays and 0.01 to 2 U/L for fluorimetric assays run at 25°C for 30 min. Convenient and high-throughput. Homogeneous "mix-incubate-measure" type assay. Can be readily automated on HTS liquid handling systems for processing thousands of samples per day. Method: OD570nm, FL530/590nm. Samples: Plasma, serum, cell and tissue etc. Species: All. Procedure: Assay takes 40 min. Kit size: 100 tests. Detection limit: 0.01 U/L.
Cell Biolabs Inc OxiSelect™ AOPP Assay Kit, 200 assays
Oxidative stress is defined as an increase in the production of reactive oxygen species (ROS) due to an imbalance between antioxidant and oxidants. Advanced Oxidation Protein Products (AOPP) are uremic toxins created during oxidative stress through the reaction of chlorinated oxidants, such as chloramines and hypochlorous acid, with plasma proteins. AOPPs are structurally similar to Advanced Glycation End-Product (AGE) proteins and exert similar biological activities. The OxiSelect™ AOPP Assay Kit offers a simple, reproducible, and consistent system for the detection of advanced oxidation protein products in plasma, lysates, and tissue homogenates. This kit includes a Chloramine standard and an AOPP Human Serum Albumin conjugate for use as a positive control. Each kit provides sufficient reagents to perform 200 tests including standard curve and unknown samples.
Cayman Chemical Cel-Based asy Glucose OxId 2mg
An ionizable cationic lipid (pKa 6.5) has been used in the generation of LNPs for the delivery of mRNA and anticancer agents in vivo LNPs containing DMT7 and encapsulating mRNA encoding Il-12 and MSA-2 decrease tumor volume lung metastatic nodule numbers and lung levels of CD4 and CD8 T cells in a 4T1 breast cancer mouse xenograft model of lung metastasis the same LNPs decrease the number of Tregs increase the number of tumor-associated M1 macrophages and increase intratumoral levels of Il-12 Il-2 Tnf-a and Ifn-? in a B16/F10 murine melanoma model
Bioworld HUMAN MACROPHAGE MIGRATION
HUMAN MACROPHAGE MIGRATION INHIBITOR FACTOR, HIS TAG N-TERMINUS (RECOMBINANT): Recombinant Human Mesoderm Inducing Factor (MIF) Source: E.Coli Background : Description The cytokine Macrophage migration inhibitory factor (MIF) has b...